Systemic lupus erythematosus

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Systemic lupus erythematosus (SLE) is a chronic, diffuse connective tissue disease caused mainly by abnormal activation of the immune system, which attacks its own tissues. The disease can damage organs throughout the body, and thus may lead to a variety of complications, including kidney damage and neuropsychiatric symptoms. We have established a stable MRLMpJ-Faslpr mouse model of SLE, which is suitable for preclinical SLE drug research and new drug evaluation.
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Disease Name	Model name	Species of animals
Disease Name	Model name	Mouse	Rat	Hamster	Guinea pig	Ferret	Rabbit	Cat	Dog	Pig	Non-human primate
Systemic lupus erythematosus	Dermatomyositis induced by myosin Fuchsin complete adjuvant combined with pertussis toxin	√
Systemic lupus erythematosus	Dermatomyositis induced by myosin Fuchsin complete adjuvant in combination with B. pertussis toxin		√		√