Complications of diabetes

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Diabetic complications are various complications that may occur after having diabetes for a long period of time, including cardiovascular disease, neuropathy, eye disease, kidney disease and so on. Diabetic patients can damage various tissues and organs due to long-term instability of blood sugar, leading to complications. Therefore, prevention and early treatment of diabetic complications are very important. We have established stable models of diabetic complications such as kidney, skin, and foot, which are suitable for the research of drugs for preclinical diabetic complications and the evaluation of new drugs.
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Disease Name	Model name	Species of animals
Disease Name	Model name	Mouse	Rat	Hamster	Guinea pig	Ferret	Rabbit	Cat	Dog	Pig	Non-human primate
High-fat diet + streptozotocin (STZ)-induced type II diabetic nephropathy model	√
db/db mouse type II diabetic nephropathy model	√
Streptozotocin (STZ)-induced peripheral vasculopathy model of type I diabetes mellitus		√
ZDF rat model of diabetic nephropathy		√
ZDF+HFD rat model of diabetic nephropathy		√
Streptozotocin (STZ)-induced cataract model of type I diabetes mellitus		√