Dermatology-Focused Preclinical CRO

KCI Biotech is a dermatology CRO providing reliable in vivo efficacy and safety testing for topical, transdermal, and systemic skin therapies. Combining deep dermatology pharmacology expertise with standardized experimental platforms, we deliver robust translational data to accelerate dermatological drug discovery.

Why Use Animal Models in Dermatology Research 

Because complex skin barrier dynamics, chronic immune responses, and tissue remodeling cannot be fully mimicked in vitro, robust dermal preclinical models are essential. Partnering with an experienced CRO in dermatology provides the controlled experimental conditions and quantifiable endpoints required to de-risk therapeutic candidates before clinical trials.

Our Portfolio of Dermatology Disease Models

KCI Biotech offers a validated suite of dermal disease models covering inflammatory, fibrotic, wound-healing, and hair disorders:

Atopic Dermatitis & Psoriasis Models

• Model of atopic dermatitis induced by calcipotriol (MC903)
• DNCB – induced atopic dermatitis model
• Oxazolidone (OXA) -induced atopic dermatitis model
• Ovalbumin (OVA)-induced model of atopic dermatitis
• Model of atopic dermatitis induced by ovalbumin (OVA) in combination with calcipotriol (MC903)
• Imiquimod (IMQ) -induced psoriasis model

Wound Healing, Fibrosis & Skin Injury Models

• Bleomycin (BLM)-induced model of systemic sclerosis
• Scar model
• Skin Scalding Model
• Skin defect healing modell
• Streptozotocin (STZ)-induced skin defect/scald model in type I diabetes mellitus
• Streptozotocin (STZ)-induced type I diabetic foot ulcer model

Comprehensive Dermatology CRO Solutions & Collaboration

KCI Biotech is a CRO with deep expertise in dermatology preclinical studies, integrating pharmacology, toxicology, and pathology to support the development of topical, transdermal, and systemic skin therapies. Our team has extensive experience in evaluating anti-inflammatory, immunomodulatory, anti-fibrotic, and wound-healing mechanisms in various dermal models.

Advanced Laboratory Animal Platforms

We operate two AAALAC-accredited animal facilities with a total area of over 40,000 m², equipped for multiple species and disease models. The facilities meet international GLP standards and are designed to support all types of in vivo dermatology research, ensuring data reliability and regulatory compliance.

Proven Track Record with Global Partners

With 1,000+ domestic and international pharmaceutical collaborations and 200+ IND submissions, KCI Biotech is recognized as a trusted preclinical CRO in dermatology research. Our established experience helps streamline study design, regulatory preparation, and translational data interpretation.

Customized Study Design & Rapid Turnaround

We tailor every study based on compound characteristics, target mechanism, and clinical translation goals. KCI Biotech offers professional CRO services to ensure that each dermatology preclinical study is both scientifically rigorous and cost-efficient.

Partner with KCI Biotech for Dermatology Drug Discovery

From model selection to data interpretation, KCI Biotech’s dermatology CRO services help bridge the gap between basic research and clinical success.

Whether your focus is topical anti-inflammatory agents, biologics, or regenerative wound care, we offer tailored protocol designs to meet your specific translational goals. Contact our scientific team today.